Metanephros

Lower Urinary Tract

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Female Reproductive System

 

 

Tissue Summary: renal proximal tubule (TS25-TS28)


About

renal proximal tubule description

Segment of the nephron linking the nephron's renal corpuscle to the loop of Henle.



View renal proximal tubule in GUDMAP Development Tutorials


In Situ Data

Link to renal proximal tubule in-situ data for TS17 Link to renal proximal tubule in-situ data for TS18 Link to renal proximal tubule in-situ data for TS19 Link to renal proximal tubule in-situ data for TS20 Link to renal proximal tubule in-situ data for TS21 Link to renal proximal tubule in-situ data for TS22 Link to renal proximal tubule in-situ data for TS23 Link to renal proximal tubule in-situ data for TS24 Link to renal proximal tubule in-situ data for TS25 Link to renal proximal tubule in-situ data for TS26 Link to renal proximal tubule in-situ data for TS27 Link to renal proximal tubule in-situ data for TS28

Validated Anchor/Marker Genes

Anchors (13)

Anchor genes are defined as genes whose expression is restricted to one temporospatial anatomical compartment. These have been selected by microarray analyses followed by validation using section in-situ hybridisation.

Gene SymbolGene MGI IDAnchor OfStageAlso Marker ofGUDMAP IDReference
Acaa1b MGI:3605455 renal proximal convoluted tubule (EMAPA:28287)
segment 2 of proximal tubule (EMAPA:29659)
TS28cortical renal tubule (EMAPA:18976)
early proximal tubule (EMAPA:28003)
immature loop of Henle (EMAPA:28049)
GUDMAP:9051
Thiagarajan et al. (2011)
AI317395 MGI:2143575 renal proximal straight tubule (EMAPA:29661)
TS28early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
GUDMAP:9157
Thiagarajan et al. (2011)
Cml1 MGI:1913366 renal proximal convoluted tubule (EMAPA:28287)
TS28early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
GUDMAP:13943
Thiagarajan et al. (2011)
Glyctk MGI:2444085 renal proximal straight tubule (EMAPA:29661)
TS28early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
GUDMAP:13505
Thiagarajan et al. (2011)
Gpd1 MGI:95679 renal proximal convoluted tubule (EMAPA:28287)
TS28cortical renal tubule (EMAPA:18976)
capillary loop renal corpuscle (EMAPA:27770)
maturing renal corpuscle (EMAPA:27943)
immature loop of Henle (EMAPA:28049)
GUDMAP:9049
Thiagarajan et al. (2011)
Hdc MGI:96062 renal proximal convoluted tubule (EMAPA:28287)
TS28cortical renal tubule (EMAPA:18976)
early proximal tubule (EMAPA:28003)
immature loop of Henle (EMAPA:28049)
GUDMAP:9163
Thiagarajan et al. (2011)
Napsa MGI:109365 renal proximal straight tubule (EMAPA:29661)
TS28early proximal tubule (EMAPA:28003)
immature loop of Henle (EMAPA:28049)
GUDMAP:10918
GUDMAP:10919
Thiagarajan et al. (2011)
Prodh2 MGI:1929093 renal proximal convoluted tubule (EMAPA:28287)
TS28early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
GUDMAP:13640
Thiagarajan et al. (2011)
Slc18a1 MGI:106684 renal proximal convoluted tubule (EMAPA:28287)
TS28early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
GUDMAP:13940
Thiagarajan et al. (2011)
Slc22a6 MGI:892001 renal proximal convoluted tubule (EMAPA:28287)
TS28early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
GUDMAP:13939
Thiagarajan et al. (2011)
Slc23a1 MGI:1341903 renal proximal straight tubule (EMAPA:29661)
TS28early proximal tubule (EMAPA:28003)
immature loop of Henle (EMAPA:28049)
GUDMAP:10931
Thiagarajan et al. (2011)
Spp2 MGI:1922646 renal proximal convoluted tubule (EMAPA:28287)
TS28early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)

Thiagarajan et al. (2011)
Ttr MGI:98865 renal proximal straight tubule (EMAPA:29661)
TS28early proximal tubule (EMAPA:28003)
immature loop of Henle (EMAPA:28049)
GUDMAP:11015
Thiagarajan et al. (2011)

 

Markers (18)

Marker genes are defined as genes which display a regional or enriched expression pattern and may be useful in identifying one or more particular temporospatial compartment(s). These have been selected by microarray analyses followed by validation using section in-situ hybridisation.

Gene SymbolGene MGI IDMarker OfStageAlso Marker OfGUDMAP IDReference
0610005C13Rik MGI:1918911 renal proximal convoluted tubule (EMAPA:28287)
renal proximal straight tubule (EMAPA:29661)
TS28early proximal tubule (EMAPA:28003)
immature loop of Henle (EMAPA:28049)
GUDMAP:13957
Thiagarajan et al. (2011)
Acsm1 MGI:2152200 renal proximal convoluted tubule (EMAPA:28287)
renal proximal straight tubule (EMAPA:29661)
TS28early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
GUDMAP:10934
Thiagarajan et al. (2011)
Apom MGI:1930124 renal proximal convoluted tubule (EMAPA:28287)
renal proximal straight tubule (EMAPA:29661)
TS28cortical renal tubule (EMAPA:18976)
early proximal tubule (EMAPA:28003)
GUDMAP:13945
Thiagarajan et al. (2011)
Bdh2 MGI:1917022 renal proximal convoluted tubule (EMAPA:28287)
renal proximal straight tubule (EMAPA:29661)
TS28early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
GUDMAP:9151
Thiagarajan et al. (2011)
Cgref1 MGI:1915817 renal proximal convoluted tubule (EMAPA:28287)
renal proximal straight tubule (EMAPA:29661)
TS28cortical renal tubule (EMAPA:18976)
early proximal tubule (EMAPA:28003)
immature loop of Henle (EMAPA:28049)
GUDMAP:9172
Thiagarajan et al. (2011)
Cryl1 MGI:1915881 renal proximal convoluted tubule (EMAPA:28287)
renal proximal straight tubule (EMAPA:29661)
TS28early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
GUDMAP:11170
Thiagarajan et al. (2011)
Fbp1 MGI:95492 renal proximal convoluted tubule (EMAPA:28287)
renal proximal straight tubule (EMAPA:29661)
TS28early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
GUDMAP:9181
Thiagarajan et al. (2011)
Fmo2 MGI:1916776 renal proximal convoluted tubule (EMAPA:28287)
renal proximal straight tubule (EMAPA:29661)
TS28early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
GUDMAP:13941
Thiagarajan et al. (2011)
Gyk MGI:106594 renal proximal convoluted tubule (EMAPA:28287)
renal proximal straight tubule (EMAPA:29661)
TS28early proximal tubule (EMAPA:28003)
early distal tubule (EMAPA:28007)
immature loop of Henle (EMAPA:28049)
GUDMAP:9154
Thiagarajan et al. (2011)
Mettl7b MGI:1918914 renal proximal convoluted tubule (EMAPA:28287)
renal proximal straight tubule (EMAPA:29661)
TS28early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
GUDMAP:9160
Thiagarajan et al. (2011)
Pter MGI:107372 renal proximal convoluted tubule (EMAPA:28287)
renal proximal straight tubule (EMAPA:29661)
TS28early proximal tubule (EMAPA:28003)
immature loop of Henle (EMAPA:28049)
GUDMAP:9143
Thiagarajan et al. (2011)
Slc27a2 MGI:1347099 renal proximal convoluted tubule (EMAPA:28287)
renal proximal straight tubule (EMAPA:29661)
TS28early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
GUDMAP:9182
Thiagarajan et al. (2011)
Slc3a1 MGI:1195264 renal proximal convoluted tubule (EMAPA:28287)
renal proximal straight tubule (EMAPA:29661)
TS28early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)

Thiagarajan et al. (2011)
Slc6a20b MGI:1336891 renal proximal convoluted tubule (EMAPA:28287)
renal proximal straight tubule (EMAPA:29661)
TS28early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
GUDMAP:10929
Thiagarajan et al. (2011)
Sord MGI:98266 renal proximal convoluted tubule (EMAPA:28287)
renal proximal straight tubule (EMAPA:29661)
TS28early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
GUDMAP:9135
Thiagarajan et al. (2011)
Tcn2 MGI:98534 renal proximal convoluted tubule (EMAPA:28287)
renal proximal straight tubule (EMAPA:29661)
TS28early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
GUDMAP:10922
Thiagarajan et al. (2011)
Ugt2b37 MGI:2148239 renal proximal convoluted tubule (EMAPA:28287)
renal proximal straight tubule (EMAPA:29661)
TS28early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
GUDMAP:9183
Thiagarajan et al. (2011)
Umod MGI:102674 renal proximal convoluted tubule (EMAPA:28287)
TS28immature loop of Henle (EMAPA:28049)
loop of Henle, inner medullary portion (EMAPA:28352)
thin ascending limb (EMAPA:28361)
distal convoluted tubule (EMAPA:28393)
distal straight tubule (EMAPA:28396)
loop of Henle (EMAPA:29665)
distal straight tubule (EMAPA:29671)
loop of Henle (EMAPA:29679)
premacula segment of distal straight tubule (EMAPA:29683)
GUDMAP:10911
GUDMAP:10912
Thiagarajan et al. (2011)

 

 

Genelists


Published Genelists

There are currently no defined published genelists for this component

 



Non-Published Genelists

There are currently no defined non-published genelists for this component