Metanephros

Lower Urinary Tract

Early Genitourinary System

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Female Reproductive System

 

 

Tissue Summary: early proximal tubule (TS21-TS27)


About

early proximal tubule description

Early tubular segment of capillary loop and maturing stage nephrons.



View early proximal tubule in GUDMAP Development Tutorials


In Situ Data

Link to early proximal tubule in-situ data for TS17 Link to early proximal tubule in-situ data for TS18 Link to early proximal tubule in-situ data for TS19 Link to early proximal tubule in-situ data for TS20 Link to early proximal tubule in-situ data for TS21 Link to early proximal tubule in-situ data for TS22 Link to early proximal tubule in-situ data for TS23 Link to early proximal tubule in-situ data for TS24 Link to early proximal tubule in-situ data for TS25 Link to early proximal tubule in-situ data for TS26 Link to early proximal tubule in-situ data for TS27 Link to early proximal tubule in-situ data for TS28

Validated Anchor/Marker Genes

Anchors (25)

Anchor genes are defined as genes whose expression is restricted to one temporospatial anatomical compartment. These have been selected by microarray analyses followed by validation using section in-situ hybridisation.

Gene SymbolGene MGI IDAnchor OfStageAlso Marker ofGUDMAP IDReference
Ace MGI:87874 early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
TS23GUDMAP:13511
Thiagarajan et al. (2011)
Acsm1 MGI:2152200 early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
TS23renal proximal convoluted tubule (EMAPA:28287)
renal proximal straight tubule (EMAPA:29661)
GUDMAP:10782
Thiagarajan et al. (2011)
AI317395 MGI:2143575 early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
TS23renal proximal straight tubule (EMAPA:29661)
GUDMAP:9158
Thiagarajan et al. (2011)
Aqp11 MGI:1913583 early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
TS23GUDMAP:13930
Thiagarajan et al. (2011)
BC089597 MGI:3583955 early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
TS23GUDMAP:13513
Thiagarajan et al. (2011)
Bdh2 MGI:1917022 early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
TS23renal proximal convoluted tubule (EMAPA:28287)
renal proximal straight tubule (EMAPA:29661)
GUDMAP:9152
Thiagarajan et al. (2011)
C2 MGI:88226 early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
TS23GUDMAP:9118
Thiagarajan et al. (2011)
Cml1 MGI:1913366 early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
TS23renal proximal convoluted tubule (EMAPA:28287)
GUDMAP:9133
Thiagarajan et al. (2011)
Cryl1 MGI:1915881 early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
TS23renal proximal convoluted tubule (EMAPA:28287)
renal proximal straight tubule (EMAPA:29661)
GUDMAP:11171
Thiagarajan et al. (2011)
Entpd5 MGI:1321385 early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
TS23GUDMAP:9175
Thiagarajan et al. (2011)
Fbp1 MGI:95492 early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
TS23renal proximal convoluted tubule (EMAPA:28287)
renal proximal straight tubule (EMAPA:29661)
GUDMAP:9177
Thiagarajan et al. (2011)
Fmo2 MGI:1916776 early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
TS23renal proximal convoluted tubule (EMAPA:28287)
renal proximal straight tubule (EMAPA:29661)
GUDMAP:9128
Thiagarajan et al. (2011)
Glyctk MGI:2444085 early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
TS23renal proximal straight tubule (EMAPA:29661)
GUDMAP:13504
Thiagarajan et al. (2011)
Mettl7b MGI:1918914 early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
TS23renal proximal convoluted tubule (EMAPA:28287)
renal proximal straight tubule (EMAPA:29661)
GUDMAP:9161
Thiagarajan et al. (2011)
Mogat2 MGI:2663253 early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
TS23GUDMAP:13580
Thiagarajan et al. (2011)
Prodh2 MGI:1929093 early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
TS23renal proximal convoluted tubule (EMAPA:28287)
GUDMAP:9124
Thiagarajan et al. (2011)
Slc18a1 MGI:106684 early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
TS23renal proximal convoluted tubule (EMAPA:28287)
GUDMAP:9039
Thiagarajan et al. (2011)
Slc22a6 MGI:892001 early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
TS23renal proximal convoluted tubule (EMAPA:28287)
GUDMAP:9116
Thiagarajan et al. (2011)
Slc27a2 MGI:1347099 early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
TS23renal proximal convoluted tubule (EMAPA:28287)
renal proximal straight tubule (EMAPA:29661)
GUDMAP:9179
Thiagarajan et al. (2011)
Slc3a1 MGI:1195264 early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
TS23renal proximal convoluted tubule (EMAPA:28287)
renal proximal straight tubule (EMAPA:29661)
GUDMAP:9141
Thiagarajan et al. (2011)
Slc6a20b MGI:1336891 early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
TS23renal proximal convoluted tubule (EMAPA:28287)
renal proximal straight tubule (EMAPA:29661)
GUDMAP:9036
Thiagarajan et al. (2011)
Sord MGI:98266 early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
TS23renal proximal convoluted tubule (EMAPA:28287)
renal proximal straight tubule (EMAPA:29661)
GUDMAP:9136
Thiagarajan et al. (2011)
Spp2 MGI:1922646 early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
TS23renal proximal convoluted tubule (EMAPA:28287)
GUDMAP:9147
Thiagarajan et al. (2011)
Tcn2 MGI:98534 early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
TS23renal proximal convoluted tubule (EMAPA:28287)
renal proximal straight tubule (EMAPA:29661)
GUDMAP:9178
Thiagarajan et al. (2011)
Ugt2b37 MGI:2148239 early proximal tubule (EMAPA:28003)
early proximal tubule of maturing nephron (EMAPA:31542)
TS23renal proximal convoluted tubule (EMAPA:28287)
renal proximal straight tubule (EMAPA:29661)
GUDMAP:9180
Thiagarajan et al. (2011)

 

Markers (27)

Marker genes are defined as genes which display a regional or enriched expression pattern and may be useful in identifying one or more particular temporospatial compartment(s). These have been selected by microarray analyses followed by validation using section in-situ hybridisation.

Gene SymbolGene MGI IDMarker OfStageAlso Marker OfGUDMAP IDReference
0610005C13Rik MGI:1918911 early proximal tubule (EMAPA:28003)
TS23immature loop of Henle (EMAPA:28049)
renal proximal convoluted tubule (EMAPA:28287)
renal proximal straight tubule (EMAPA:29661)
GUDMAP:13955
Thiagarajan et al. (2011)
2310046K01Rik MGI:1916948 early proximal tubule (EMAPA:28003)
TS23immature loop of Henle (EMAPA:28049)
GUDMAP:10780
Thiagarajan et al. (2011)
Aadac MGI:1915008 early proximal tubule (EMAPA:28003)
TS23cortical renal tubule (EMAPA:18976)
immature loop of Henle (EMAPA:28049)
GUDMAP:9034
Thiagarajan et al. (2011)
Acaa1b MGI:3605455 early proximal tubule (EMAPA:28003)
TS23cortical renal tubule (EMAPA:18976)
immature loop of Henle (EMAPA:28049)
renal proximal convoluted tubule (EMAPA:28287)
segment 2 of proximal tubule (EMAPA:29659)
GUDMAP:9040
Thiagarajan et al. (2011)
Aldh1l1 MGI:1340024 early proximal tubule (EMAPA:28003)
TS23early distal tubule (EMAPA:28007)
immature loop of Henle (EMAPA:28049)
GUDMAP:13954
Thiagarajan et al. (2011)
Ambp MGI:88002 early proximal tubule (EMAPA:28003)
TS23immature loop of Henle (EMAPA:28049)
GUDMAP:13579
Thiagarajan et al. (2011)
Apom MGI:1930124 early proximal tubule (EMAPA:28003)
TS23cortical renal tubule (EMAPA:18976)
renal proximal convoluted tubule (EMAPA:28287)
renal proximal straight tubule (EMAPA:29661)
GUDMAP:10784
Thiagarajan et al. (2011)
Cgref1 MGI:1915817 early proximal tubule (EMAPA:28003)
TS23cortical renal tubule (EMAPA:18976)
immature loop of Henle (EMAPA:28049)
renal proximal convoluted tubule (EMAPA:28287)
renal proximal straight tubule (EMAPA:29661)
GUDMAP:9173
Thiagarajan et al. (2011)
Cideb MGI:1270844 early proximal tubule (EMAPA:28003)
TS23cortical renal tubule (EMAPA:18976)
immature loop of Henle (EMAPA:28049)
GUDMAP:9166
Thiagarajan et al. (2011)
Clic6 MGI:2146607 early proximal tubule (EMAPA:28003)
TS23immature loop of Henle (EMAPA:28049)
GUDMAP:9149
Thiagarajan et al. (2011)
Dpep1 MGI:94917 early proximal tubule (EMAPA:28003)
TS23maturing renal corpuscle (EMAPA:27943)
GUDMAP:9126
Thiagarajan et al. (2011)
Fbp2 MGI:95491 early proximal tubule (EMAPA:28003)
TS23immature loop of Henle (EMAPA:28049)
GUDMAP:13581
Thiagarajan et al. (2011)
Gyk MGI:106594 early proximal tubule (EMAPA:28003)
TS23early distal tubule (EMAPA:28007)
immature loop of Henle (EMAPA:28049)
renal proximal convoluted tubule (EMAPA:28287)
renal proximal straight tubule (EMAPA:29661)
GUDMAP:9155
Thiagarajan et al. (2011)
Hdc MGI:96062 early proximal tubule (EMAPA:28003)
TS23cortical renal tubule (EMAPA:18976)
immature loop of Henle (EMAPA:28049)
renal proximal convoluted tubule (EMAPA:28287)
GUDMAP:9164
Thiagarajan et al. (2011)
Myo15b MGI:2685534 early proximal tubule (EMAPA:28003)
TS23cortical renal tubule (EMAPA:18976)
immature loop of Henle (EMAPA:28049)
GUDMAP:9038
Thiagarajan et al. (2011)
Napsa MGI:109365 early proximal tubule (EMAPA:28003)
TS23immature loop of Henle (EMAPA:28049)
renal proximal straight tubule (EMAPA:29661)
GUDMAP:10917
Thiagarajan et al. (2011)
Pipox MGI:1197006 early proximal tubule (EMAPA:28003)
TS23cortical renal tubule (EMAPA:18976)
immature loop of Henle (EMAPA:28049)
GUDMAP:10786
Thiagarajan et al. (2011)
Pter MGI:107372 early proximal tubule (EMAPA:28003)
TS23immature loop of Henle (EMAPA:28049)
renal proximal convoluted tubule (EMAPA:28287)
renal proximal straight tubule (EMAPA:29661)
GUDMAP:8210
Thiagarajan et al. (2011)
Serpina10 MGI:2667725 early proximal tubule (EMAPA:28003)
TS23immature loop of Henle (EMAPA:28049)
GUDMAP:9131
Thiagarajan et al. (2011)
Sigirr MGI:1344402 early proximal tubule (EMAPA:28003)
TS23early distal tubule (EMAPA:28007)
immature loop of Henle (EMAPA:28049)
GUDMAP:10776
Thiagarajan et al. (2011)
Slc23a1 MGI:1341903 early proximal tubule (EMAPA:28003)
TS23immature loop of Henle (EMAPA:28049)
renal proximal straight tubule (EMAPA:29661)
GUDMAP:9176
Thiagarajan et al. (2011)
Slc6a13 MGI:95629 early proximal tubule (EMAPA:28003)
TS23cortical renal tubule (EMAPA:18976)
immature loop of Henle (EMAPA:28049)
GUDMAP:9168
Thiagarajan et al. (2011)
Susd3 MGI:1913579 early proximal tubule (EMAPA:28003)
TS23cortical renal tubule (EMAPA:18976)
immature loop of Henle (EMAPA:28049)
GUDMAP:13582
Thiagarajan et al. (2011)
Ttc36 MGI:2384760 early proximal tubule (EMAPA:28003)
TS23cortical renal tubule (EMAPA:18976)
immature loop of Henle (EMAPA:28049)
GUDMAP:13583
GUDMAP:13704
Thiagarajan et al. (2011)
Ttr MGI:98865 early proximal tubule (EMAPA:28003)
TS23immature loop of Henle (EMAPA:28049)
renal proximal straight tubule (EMAPA:29661)
GUDMAP:11016
Thiagarajan et al. (2011)
Unc5cl MGI:1923839 early proximal tubule (EMAPA:28003)
TS23cortical renal tubule (EMAPA:18976)
immature loop of Henle (EMAPA:28049)
GUDMAP:13938
Thiagarajan et al. (2011)
Vdr MGI:103076 early proximal tubule (EMAPA:28003)
TS23GUDMAP:13935
Thiagarajan et al. (2011)

 

 

Genelists


Published Genelists

Published genelists from Microarray Analysis. Click on the number of probes to go to heatmap view


List NameDescription EntitiesGenesSubmitted ByRefs
UQ Early Proximal Tubule E15.5Anchor genes specific to key renal compartments: Early Proximal Tubule E15.578 probesets76Kylie Georgas, Rathi ThiagarajanThiagarajan et al. (2011)
Proximal Tubules 15.5dpcBrunskill et al.: Proximal Tubules 15.5dpc640 probesets433Bruce Aronow, Eric BrunskillBrunskill et al. (2008)
K-means clustered - all from Brunskill et al. (2008)Brunskill et al.: All k-means clustered probesets7599 probesets4757Bruce Aronow, Eric BrunskillBrunskill et al. (2008)

 



Non-Published Genelists

Non-published genelists from Microarray Analysis. Click on the list name or number of probes to go to heatmap view. Microarray Analysis Help.


List NameDescription EntitiesGenesSubmitted ByRefs
DevelopingKidney_e15.5_early proxim tubul_emap-28005_100100 probesets86Bruce Aronow
DevelopingKidney_e15.5_early proxim tubul_emap-28005_10001000 probesets846Bruce Aronow
DevelopingKidney_e15.5_early proxim tubul_emap-28005_200200 probesets176Bruce Aronow
DevelopingKidney_e15.5_early proxim tubul_emap-28005_500500 probesets435Bruce Aronow
DevelopingKidney_e15.5_early proxim tubul_emap-28005_k1_1004 probesets4Bruce Aronow
DevelopingKidney_e15.5_early proxim tubul_emap-28005_k1_1000227 probesets210Bruce Aronow
DevelopingKidney_e15.5_early proxim tubul_emap-28005_k1_20054 probesets50Bruce Aronow
DevelopingKidney_e15.5_early proxim tubul_emap-28005_k1_500112 probesets102Bruce Aronow
DevelopingKidney_e15.5_early proxim tubul_emap-28005_k2_10034 probesets32Bruce Aronow
DevelopingKidney_e15.5_early proxim tubul_emap-28005_k2_1000100 probesets83Bruce Aronow
DevelopingKidney_e15.5_early proxim tubul_emap-28005_k2_20011 probesets10Bruce Aronow
DevelopingKidney_e15.5_early proxim tubul_emap-28005_k2_50045 probesets41Bruce Aronow
DevelopingKidney_e15.5_early proxim tubul_emap-28005_k3_10038 probesets36Bruce Aronow
DevelopingKidney_e15.5_early proxim tubul_emap-28005_k3_1000182 probesets168Bruce Aronow
DevelopingKidney_e15.5_early proxim tubul_emap-28005_k3_20051 probesets48Bruce Aronow
DevelopingKidney_e15.5_early proxim tubul_emap-28005_k3_500101 probesets91Bruce Aronow
DevelopingKidney_e15.5_early proxim tubul_emap-28005_k4_10014 probesets12Bruce Aronow
DevelopingKidney_e15.5_early proxim tubul_emap-28005_k4_1000216 probesets185Bruce Aronow
DevelopingKidney_e15.5_early proxim tubul_emap-28005_k4_20035 probesets29Bruce Aronow
DevelopingKidney_e15.5_early proxim tubul_emap-28005_k4_500125 probesets113Bruce Aronow
DevelopingKidney_e15.5_early proxim tubul_emap-28005_k5_10010 probesets7Bruce Aronow
DevelopingKidney_e15.5_early proxim tubul_emap-28005_k5_1000275 probesets247Bruce Aronow
DevelopingKidney_e15.5_early proxim tubul_emap-28005_k5_20049 probesets46Bruce Aronow
DevelopingKidney_e15.5_early proxim tubul_emap-28005_k5_500117 probesets111Bruce Aronow
DevelopingKidney_e15.5_Proximal Tubules_emap-28005_100100 probesets87Bruce Aronow
DevelopingKidney_e15.5_Proximal Tubules_emap-28005_10001000 probesets829Bruce Aronow
DevelopingKidney_e15.5_Proximal Tubules_emap-28005_200200 probesets168Bruce Aronow
DevelopingKidney_e15.5_Proximal Tubules_emap-28005_500500 probesets424Bruce Aronow
DevelopingKidney_e15.5_Proximal Tubules_emap-28005_k1_10032 probesets28Bruce Aronow
DevelopingKidney_e15.5_Proximal Tubules_emap-28005_k1_1000122 probesets107Bruce Aronow
DevelopingKidney_e15.5_Proximal Tubules_emap-28005_k1_20049 probesets45Bruce Aronow
DevelopingKidney_e15.5_Proximal Tubules_emap-28005_k1_500113 probesets106Bruce Aronow
DevelopingKidney_e15.5_Proximal Tubules_emap-28005_k2_1004 probesets2Bruce Aronow
DevelopingKidney_e15.5_Proximal Tubules_emap-28005_k2_100090 probesets83Bruce Aronow
DevelopingKidney_e15.5_Proximal Tubules_emap-28005_k2_20030 probesets28Bruce Aronow
DevelopingKidney_e15.5_Proximal Tubules_emap-28005_k2_50064 probesets60Bruce Aronow
DevelopingKidney_e15.5_Proximal Tubules_emap-28005_k3_10030 probesets28Bruce Aronow
DevelopingKidney_e15.5_Proximal Tubules_emap-28005_k3_1000175 probesets162Bruce Aronow
DevelopingKidney_e15.5_Proximal Tubules_emap-28005_k3_20010 probesets8Bruce Aronow
DevelopingKidney_e15.5_Proximal Tubules_emap-28005_k3_50055 probesets48Bruce Aronow
DevelopingKidney_e15.5_Proximal Tubules_emap-28005_k4_1002 probesets2Bruce Aronow
DevelopingKidney_e15.5_Proximal Tubules_emap-28005_k4_1000249 probesets228Bruce Aronow
DevelopingKidney_e15.5_Proximal Tubules_emap-28005_k4_20061 probesets56Bruce Aronow
DevelopingKidney_e15.5_Proximal Tubules_emap-28005_k4_500114 probesets106Bruce Aronow
DevelopingKidney_e15.5_Proximal Tubules_emap-28005_k5_10032 probesets31Bruce Aronow
DevelopingKidney_e15.5_Proximal Tubules_emap-28005_k5_1000364 probesets308Bruce Aronow
DevelopingKidney_e15.5_Proximal Tubules_emap-28005_k5_20050 probesets46Bruce Aronow
DevelopingKidney_e15.5_Proximal Tubules_emap-28005_k5_500154 probesets134Bruce Aronow