Metanephros

Lower Urinary Tract

Early Genitourinary System

Male Reproductive System

Female Reproductive System

 

 

Tissue Summary: comma-shaped body (TS20-TS27)


About

comma-shaped body description

The renal vesicle grows and differentiates further and changes morphology. The proximal portion elongates and a cleft appears, giving it a comma shape. The comma-shaped body is a transitional nephron stage and is subdivided into connecting segment and distal and proximal segments (upper and lower limb respectively).



View comma-shaped body in GUDMAP Development Tutorials


In Situ Data

Link to comma-shaped body in-situ data for TS17 Link to comma-shaped body in-situ data for TS18 Link to comma-shaped body in-situ data for TS19 Link to comma-shaped body in-situ data for TS20 Link to comma-shaped body in-situ data for TS21 Link to comma-shaped body in-situ data for TS22 Link to comma-shaped body in-situ data for TS23 Link to comma-shaped body in-situ data for TS24 Link to comma-shaped body in-situ data for TS25 Link to comma-shaped body in-situ data for TS26 Link to comma-shaped body in-situ data for TS27 Link to comma-shaped body in-situ data for TS28

Validated Anchor/Marker Genes

Anchors (1)

Anchor genes are defined as genes whose expression is restricted to one temporospatial anatomical compartment. These have been selected by microarray analyses followed by validation using section in-situ hybridisation.

Gene SymbolGene MGI IDAnchor OfStageAlso Marker ofGUDMAP IDReference
Npy MGI:97374 comma-shaped body (EMAPA:27681)
TS23renal vesicle (EMAPA:27678)
early tubule (EMAPA:28500)
GUDMAP:8964
Thiagarajan et al. (2011)

 

Markers (15)

Marker genes are defined as genes which display a regional or enriched expression pattern and may be useful in identifying one or more particular temporospatial compartment(s). These have been selected by microarray analyses followed by validation using section in-situ hybridisation.

Gene SymbolGene MGI IDMarker OfStageAlso Marker OfGUDMAP IDReference
Bmp2 MGI:88177 comma-shaped body (EMAPA:27681)
TS23renal vesicle (EMAPA:27678)
s-shaped body (EMAPA:27756)
renal connecting tubule of s-shaped body (EMAPA:27758)
distal segment of s-shaped body (EMAPA:27760)
medial segment of s-shaped body (EMAPA:27762)
early tubule (EMAPA:28500)
renal connecting segment of renal vesicle (EMAPA:31541)
distal renal vesicle (EMAPA:31582)
GUDMAP:8949
Georgas et al. (2009)
Thiagarajan et al. (2011)
Ccnd1 MGI:88313 comma-shaped body (EMAPA:27681)
TS23pretubular aggregate (EMAPA:27673)
renal vesicle (EMAPA:27678)
s-shaped body (EMAPA:27756)
renal connecting tubule of s-shaped body (EMAPA:27758)
distal segment of s-shaped body (EMAPA:27760)
medial segment of s-shaped body (EMAPA:27762)
early tubule (EMAPA:28500)
GUDMAP:11180
Georgas et al. (2009)
Cdh4 MGI:99218 comma-shaped body (EMAPA:27681)
TS23pretubular aggregate (EMAPA:27673)
renal vesicle (EMAPA:27678)
s-shaped body (EMAPA:27756)
early tubule (EMAPA:28500)
GUDMAP:7822
Georgas et al. (2009)
Cdh6 MGI:107435 comma-shaped body (EMAPA:27681)
TS23renal vesicle (EMAPA:27678)
s-shaped body (EMAPA:27756)
medial segment of s-shaped body (EMAPA:27762)
early tubule (EMAPA:28500)
GUDMAP:11368
Georgas et al. (2009)
Dkk1 MGI:1329040 comma-shaped body (EMAPA:27681)
TS23renal vesicle (EMAPA:27678)
s-shaped body (EMAPA:27756)
medial segment of s-shaped body (EMAPA:27762)
early tubule (EMAPA:28500)
distal renal vesicle (EMAPA:31582)
GUDMAP:9045
Georgas et al. (2009)
Dll1 MGI:104659 comma-shaped body (EMAPA:27681)
TS23pretubular aggregate (EMAPA:27673)
renal vesicle (EMAPA:27678)
s-shaped body (EMAPA:27756)
medial segment of s-shaped body (EMAPA:27762)
early tubule (EMAPA:28500)
distal renal vesicle (EMAPA:31582)
GUDMAP:11371
Georgas et al. (2009)
Greb1 MGI:2149712 comma-shaped body (EMAPA:27681)
TS23pretubular aggregate (EMAPA:27673)
renal vesicle (EMAPA:27678)
s-shaped body (EMAPA:27756)
medial segment of s-shaped body (EMAPA:27762)
early tubule (EMAPA:28500)
distal renal vesicle (EMAPA:31582)
GUDMAP:8891
Georgas et al. (2009)
Jag1 MGI:1095416 comma-shaped body (EMAPA:27681)
TS23renal vesicle (EMAPA:27678)
s-shaped body (EMAPA:27756)
medial segment of s-shaped body (EMAPA:27762)
early tubule (EMAPA:28500)
GUDMAP:8957
Georgas et al. (2009)
Lhx1 MGI:99783 comma-shaped body (EMAPA:27681)
TS23pretubular aggregate (EMAPA:27673)
renal vesicle (EMAPA:27678)
s-shaped body (EMAPA:27756)
distal segment of s-shaped body (EMAPA:27760)
medial segment of s-shaped body (EMAPA:27762)
early tubule (EMAPA:28500)
renal connecting segment of renal vesicle (EMAPA:31541)
distal renal vesicle (EMAPA:31582)
GUDMAP:13416
GUDMAP:7928
GUDMAP:8211
Georgas et al. (2009)
Thiagarajan et al. (2011)
Papss2 MGI:1330223 comma-shaped body (EMAPA:27681)
TS23renal vesicle (EMAPA:27678)
s-shaped body (EMAPA:27756)
medial segment of s-shaped body (EMAPA:27762)
early tubule (EMAPA:28500)
distal renal vesicle (EMAPA:31582)
GUDMAP:8960
Georgas et al. (2009)
Pcsk9 MGI:2140260 comma-shaped body (EMAPA:27681)
TS23renal vesicle (EMAPA:27678)
s-shaped body (EMAPA:27756)
medial segment of s-shaped body (EMAPA:27762)
early tubule (EMAPA:28500)
distal renal vesicle (EMAPA:31582)
GUDMAP:8962
Georgas et al. (2009)
Pou3f3 MGI:102564 comma-shaped body (EMAPA:27681)
TS23renal vesicle (EMAPA:27678)
s-shaped body (EMAPA:27756)
renal connecting tubule of s-shaped body (EMAPA:27758)
distal segment of s-shaped body (EMAPA:27760)
medial segment of s-shaped body (EMAPA:27762)
early tubule (EMAPA:28500)
renal connecting segment of renal vesicle (EMAPA:31541)
distal renal vesicle (EMAPA:31582)
GUDMAP:13707
Georgas et al. (2009)
Tmem100 MGI:1915138 comma-shaped body (EMAPA:27681)
TS23pretubular aggregate (EMAPA:27673)
renal vesicle (EMAPA:27678)
s-shaped body (EMAPA:27756)
proximal segment of s-shaped body (EMAPA:27764)
parietal epithelium of s-shaped body (EMAPA:27768)
early tubule (EMAPA:28500)
proximal renal vesicle (EMAPA:31549)
GUDMAP:8888
GUDMAP:8886
Georgas et al. (2009)
Thiagarajan et al. (2011)
Wnt4 MGI:98957 comma-shaped body (EMAPA:27681)
TS23pretubular aggregate (EMAPA:27673)
renal vesicle (EMAPA:27678)
s-shaped body (EMAPA:27756)
medial segment of s-shaped body (EMAPA:27762)
early tubule (EMAPA:28500)
GUDMAP:7156
GUDMAP:8208
GUDMAP:8209
Georgas et al. (2009)
Thiagarajan et al. (2011)
Wt1 MGI:98968 comma-shaped body (EMAPA:27681)
TS23pretubular aggregate (EMAPA:27673)
renal vesicle (EMAPA:27678)
s-shaped body (EMAPA:27756)
proximal segment of s-shaped body (EMAPA:27764)
early tubule (EMAPA:28500)
proximal renal vesicle (EMAPA:31549)
GUDMAP:8200
Georgas et al. (2009)

 

 

Genelists


Published Genelists

There are currently no defined published genelists for this component

 



Non-Published Genelists

There are currently no defined non-published genelists for this component