Metanephros

Lower Urinary Tract

Early Genitourinary System

Male Reproductive System

Female Reproductive System

 

 

Tissue Summary: s-shaped body (TS21-TS27)


About

s-shaped body description

The comma-shaped body elongates, folds and acquires an S shape. The S-shaped nephron, connected to the ureteric tip via a renal connecting tubule, has differentiated into additional molecular regions and can be further subdivided into proximal, medial and distal segments.



View s-shaped body in GUDMAP Development Tutorials


In Situ Data

Link to s-shaped body in-situ data for TS17 Link to s-shaped body in-situ data for TS18 Link to s-shaped body in-situ data for TS19 Link to s-shaped body in-situ data for TS20 Link to s-shaped body in-situ data for TS21 Link to s-shaped body in-situ data for TS22 Link to s-shaped body in-situ data for TS23 Link to s-shaped body in-situ data for TS24 Link to s-shaped body in-situ data for TS25 Link to s-shaped body in-situ data for TS26 Link to s-shaped body in-situ data for TS27 Link to s-shaped body in-situ data for TS28

Validated Anchor/Marker Genes

Anchors (0)

Anchor genes are defined as genes whose expression is restricted to one temporospatial anatomical compartment. These have been selected by microarray analyses followed by validation using section in-situ hybridisation.

Currently no defined anchor genes for this component

 

Markers (17)

Marker genes are defined as genes which display a regional or enriched expression pattern and may be useful in identifying one or more particular temporospatial compartment(s). These have been selected by microarray analyses followed by validation using section in-situ hybridisation.

Gene SymbolGene MGI IDMarker OfStageAlso Marker OfGUDMAP IDReference
Bmp2 MGI:88177 s-shaped body (EMAPA:27756)
distal segment of s-shaped body (EMAPA:27760)
medial segment of s-shaped body (EMAPA:27762)
renal connecting tubule of s-shaped body (EMAPA:27758)
TS23renal vesicle (EMAPA:27678)
comma-shaped body (EMAPA:27681)
early tubule (EMAPA:28500)
renal connecting segment of renal vesicle (EMAPA:31541)
distal renal vesicle (EMAPA:31582)
GUDMAP:8949
Georgas et al. (2009)
Thiagarajan et al. (2011)
Ccnd1 MGI:88313 s-shaped body (EMAPA:27756)
renal connecting tubule of s-shaped body (EMAPA:27758)
distal segment of s-shaped body (EMAPA:27760)
medial segment of s-shaped body (EMAPA:27762)
TS23pretubular aggregate (EMAPA:27673)
renal vesicle (EMAPA:27678)
comma-shaped body (EMAPA:27681)
early tubule (EMAPA:28500)
GUDMAP:11180
Georgas et al. (2009)
Cdh4 MGI:99218 s-shaped body (EMAPA:27756)
TS23pretubular aggregate (EMAPA:27673)
renal vesicle (EMAPA:27678)
comma-shaped body (EMAPA:27681)
early tubule (EMAPA:28500)
GUDMAP:7822
Georgas et al. (2009)
Cdh6 MGI:107435 s-shaped body (EMAPA:27756)
medial segment of s-shaped body (EMAPA:27762)
TS23renal vesicle (EMAPA:27678)
comma-shaped body (EMAPA:27681)
early tubule (EMAPA:28500)
GUDMAP:11368
Georgas et al. (2009)
Dkk1 MGI:1329040 s-shaped body (EMAPA:27756)
medial segment of s-shaped body (EMAPA:27762)
TS23renal vesicle (EMAPA:27678)
comma-shaped body (EMAPA:27681)
early tubule (EMAPA:28500)
distal renal vesicle (EMAPA:31582)
GUDMAP:9045
Georgas et al. (2009)
Dll1 MGI:104659 s-shaped body (EMAPA:27756)
medial segment of s-shaped body (EMAPA:27762)
TS23pretubular aggregate (EMAPA:27673)
renal vesicle (EMAPA:27678)
comma-shaped body (EMAPA:27681)
early tubule (EMAPA:28500)
distal renal vesicle (EMAPA:31582)
GUDMAP:11371
Georgas et al. (2009)
Greb1 MGI:2149712 s-shaped body (EMAPA:27756)
medial segment of s-shaped body (EMAPA:27762)
TS23pretubular aggregate (EMAPA:27673)
renal vesicle (EMAPA:27678)
comma-shaped body (EMAPA:27681)
early tubule (EMAPA:28500)
distal renal vesicle (EMAPA:31582)
GUDMAP:8891
Georgas et al. (2009)
Jag1 MGI:1095416 s-shaped body (EMAPA:27756)
medial segment of s-shaped body (EMAPA:27762)
TS23renal vesicle (EMAPA:27678)
comma-shaped body (EMAPA:27681)
early tubule (EMAPA:28500)
GUDMAP:8957
Georgas et al. (2009)
Lhx1 MGI:99783 s-shaped body (EMAPA:27756)
medial segment of s-shaped body (EMAPA:27762)
distal segment of s-shaped body (EMAPA:27760)
TS23pretubular aggregate (EMAPA:27673)
renal vesicle (EMAPA:27678)
comma-shaped body (EMAPA:27681)
early tubule (EMAPA:28500)
renal connecting segment of renal vesicle (EMAPA:31541)
distal renal vesicle (EMAPA:31582)
GUDMAP:13416
GUDMAP:7928
GUDMAP:8211
Georgas et al. (2009)
Thiagarajan et al. (2011)
Papss2 MGI:1330223 s-shaped body (EMAPA:27756)
medial segment of s-shaped body (EMAPA:27762)
TS23renal vesicle (EMAPA:27678)
comma-shaped body (EMAPA:27681)
early tubule (EMAPA:28500)
distal renal vesicle (EMAPA:31582)
GUDMAP:8960
Georgas et al. (2009)
Pcsk9 MGI:2140260 s-shaped body (EMAPA:27756)
medial segment of s-shaped body (EMAPA:27762)
TS23renal vesicle (EMAPA:27678)
comma-shaped body (EMAPA:27681)
early tubule (EMAPA:28500)
distal renal vesicle (EMAPA:31582)
GUDMAP:8962
Georgas et al. (2009)
Pou3f3 MGI:102564 s-shaped body (EMAPA:27756)
renal connecting tubule of s-shaped body (EMAPA:27758)
medial segment of s-shaped body (EMAPA:27762)
distal segment of s-shaped body (EMAPA:27760)
TS23renal vesicle (EMAPA:27678)
comma-shaped body (EMAPA:27681)
early tubule (EMAPA:28500)
renal connecting segment of renal vesicle (EMAPA:31541)
distal renal vesicle (EMAPA:31582)
GUDMAP:13707
Georgas et al. (2009)
Sox9 MGI:98371 s-shaped body (EMAPA:27756)
TS23cortical renal tubule (EMAPA:18976)
ureteric tip (EMAPA:27605)
renal vesicle (EMAPA:27678)
GUDMAP:20765
Thiagarajan et al. (2011)
Stc2 MGI:1316731 s-shaped body (EMAPA:27756)
TS23capillary loop renal corpuscle (EMAPA:27770)
maturing renal corpuscle (EMAPA:27943)
GUDMAP:13703
Thiagarajan et al. (2011)
Tmem100 MGI:1915138 s-shaped body (EMAPA:27756)
proximal segment of s-shaped body (EMAPA:27764)
parietal epithelium of s-shaped body (EMAPA:27768)
TS23pretubular aggregate (EMAPA:27673)
renal vesicle (EMAPA:27678)
comma-shaped body (EMAPA:27681)
early tubule (EMAPA:28500)
proximal renal vesicle (EMAPA:31549)
GUDMAP:8888
GUDMAP:8886
Georgas et al. (2009)
Thiagarajan et al. (2011)
Wnt4 MGI:98957 s-shaped body (EMAPA:27756)
medial segment of s-shaped body (EMAPA:27762)
TS23pretubular aggregate (EMAPA:27673)
renal vesicle (EMAPA:27678)
comma-shaped body (EMAPA:27681)
early tubule (EMAPA:28500)
GUDMAP:7156
GUDMAP:8208
GUDMAP:8209
Georgas et al. (2009)
Thiagarajan et al. (2011)
Wt1 MGI:98968 s-shaped body (EMAPA:27756)
proximal segment of s-shaped body (EMAPA:27764)
TS23pretubular aggregate (EMAPA:27673)
renal vesicle (EMAPA:27678)
comma-shaped body (EMAPA:27681)
early tubule (EMAPA:28500)
proximal renal vesicle (EMAPA:31549)
GUDMAP:8200
Georgas et al. (2009)

 

 

Genelists


Published Genelists

Published genelists from Microarray Analysis. Click on the number of probes to go to heatmap view


List NameDescription EntitiesGenesSubmitted ByRefs
UQ S-Shaped Body E15.5Anchor genes specific to key renal compartments: S-Shaped Body E15.52 probesets2Kylie Georgas, Rathi ThiagarajanThiagarajan et al. (2011)
S-Shaped Body 15.5dpcBrunskill et al.: S-Shaped Body 15.5dpc642 probesets531Bruce Aronow, Eric BrunskillBrunskill et al. (2008)
K-means clustered - all from Brunskill et al. (2008)Brunskill et al.: All k-means clustered probesets7599 probesets4757Bruce Aronow, Eric BrunskillBrunskill et al. (2008)

 



Non-Published Genelists

Non-published genelists from Microarray Analysis. Click on the list name or number of probes to go to heatmap view. Microarray Analysis Help.


List NameDescription EntitiesGenesSubmitted ByRefs
DevelopingKidney_e15.5_S-shaped body_emap-27855_100100 probesets87Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_10001000 probesets860Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_200200 probesets174Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_500500 probesets438Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k1_1009 probesets8Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k1_1000253 probesets224Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k1_20043 probesets40Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k1_50094 probesets82Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k2_10033 probesets28Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k2_1000215 probesets195Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k2_20033 probesets32Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k2_500123 probesets111Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k3_10023 probesets21Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k3_1000225 probesets195Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k3_20013 probesets11Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k3_50083 probesets78Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k4_10018 probesets17Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k4_1000144 probesets129Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k4_20052 probesets44Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k4_500111 probesets98Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k5_10017 probesets15Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k5_1000163 probesets157Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k5_20059 probesets50Bruce Aronow
DevelopingKidney_e15.5_S-shaped body_emap-27855_k5_50089 probesets81Bruce Aronow
SS 102S-Shaped Body102 probesets80Bruce Aronowno ref