A high-resolution ontology has been developed by members of the GUDMAP consortium to describe the subcompartments of the developing murine genitourinary tract (Little et al., 2007).
This ontology incorporates what can be defined histologically and begins to encompass other structures and cell types already identified at the molecular level.
The GUDMAP ontology encompasses Theiler stage (TS) 17-27 of development as well as the sexually mature adult. It has been written as a partonomic, text-based, hierarchical ontology that, for the embryological stages, has been developed as a high-resolution expansion of the existing Edinburgh Mouse Atlas Project (EMAP) ontology.
The original published GUDMAP ontology listed anatomical terms for each TS separately, with every term appended with a unique stage-specific numerical identifier (EMAP:ID). An “abstract” (non stage-specific) version of the ontology has subsequently been developed with each anatomical term given an EMAPA:ID and TS range, indicating the developmental period that the term is present (Hayamizu et al., 2013).
Synonyms have been used to improve the success of query searching and maintain wherever possible exisitng EMAP terms relating to this organ system.
An illustrated anatomical ontology of the developing mouse lower urinary tract - Georgas et al. 2015. Development. 142(10):1893-908.
Link to associated supplementary documents and ontology
Interactive tree of the developing murine genitourinary ontology
Click the following links to retrieve archived versions of the ontology